The ITGA2B antibody - N-terminal region (ARP63955_P050) from Aviva Systems Biology is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The ITGA2B antibody - N-terminal region (ARP63955_P050) has been validated for the following applications: Western Blot.
Description
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling